Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome.
Epigenetic cellular memory mechanisms that involve polycomb and trithorax group of proteins are well conserved across metazoans.The cis-acting elements interacting with these proteins, however, are poorly understood in mammals.In a directed search we identified a potential polycomb responsive element with read more 25 repeats of YY1 binding motifth